7-OXY
7-Hydroxymitragynine has been scientifically shown to interact with OPIOID RECEPTORS in the brain and are classified as indole alkaloids. Extracted from the foliage of the Mitragyna speciosa, 7-Hydroxymitragynine is an exceptional alkaloid boasting intriguing characteristics. Farma Barn’s 7-OXY offers novel plant based gel capsules for maximum absorbsion and instant relief with the purest 7-Hydroxymitragynine.
“You don’t understand… The pain is gone”. -Quote from another satisfied customer
$11.99 – $38.99
7-Hydroxymitragynine has been scientifically shown to interact with OPIOID RECEPTORS in the brain and are classified as indole alkaloids. Extracted from the foliage of the Mitragyna speciosa, 7-Hydroxymitragynine is an exceptional alkaloid boasting intriguing characteristics. Farma Barn’s 7-OXY offers novel plant based gel capsules for maximum absorbsion and instant relief with the purest 7-Hydroxymitragynine.
“You don’t understand… The pain is gone”. -Quote from another satisfied customer
69.6% Snow-Caps… these bad-boys are no joke! For the experienced user for sure:-)
Take your drinks to the next level with Farma Barn’s Delta 9 Beverage Enhancer. Unlike other products on the market, our water-soluble Beverage Enhancer utilizes cutting-edge hemp nanoparticles, which absorb into your system at a rate twice as fast and hit five times as hard as competing products. Mix one or two squirts into your favorite drink or cocktail for a tasty way to enjoy a legal Delta 9 THC experience.
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Chemical Structure: It is an oxidation product of mitragynine, the primary psychoactive alkaloid in kratom. Structurally, it includes a hydroxyl group at the 7-position of the mitragynine molecule, which significantly alters its potency and effects.
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Pharmacological Activity:
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7-Hydroxymitragynine acts as a potent mu-opioid receptor agonist, which means it binds to and activates these receptors in the brain, leading to effects similar to traditional opioids but with some differences in receptor activation profiles.
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It shows partial agonist activity at the mu-opioid receptor, meaning it doesn’t activate these receptors to the full extent that morphine does.
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Unlike traditional opioids, 7-hydroxymitragynine does not significantly recruit β-arrestin, which is linked to many of the adverse effects like respiratory depression, constipation, and sedation.
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Potency and Effects:
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Research has indicated that 7-hydroxymitragynine is much more potent than mitragynine, with some studies suggesting it’s about 13 times more potent than morphine in terms of its analgesic effects.
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It has been identified as a key mediator of the analgesic properties observed with kratom use. Its potency and activity profile suggest it might contribute significantly to kratom’s pain-relieving effects.
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Metabolism:
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7-Hydroxymitragynine is formed in vivo from mitragynine through hepatic metabolism, specifically via cytochrome P450 3A4 enzymes. This conversion enhances the analgesic effects of kratom.
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Interestingly, it can also convert back to mitragynine in human liver microsomes, indicating a dynamic metabolic relationship between these two compounds.
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Potential Uses and Concerns:
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Due to its potency, there’s interest in 7-hydroxymitragynine for pain management, potentially offering analgesia with fewer side effects compared to traditional opioids.
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However, there are concerns regarding its potential for addiction, abuse, and the development of tolerance. It’s also noted for its potential to cause opioid-like withdrawal symptoms upon cessation, though these might be less severe compared to traditional opioids.
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Legal Status and Public Health:
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While kratom and its derivatives like 7-hydroxymitragynine are not universally regulated, there’s ongoing debate regarding their legal status due to safety and abuse potential.
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In areas where kratom is legal, the sale or use of potent extracts containing high levels of 7-hydroxymitragynine might be viewed with caution due to their enhanced opioid-like effects.
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| 7-OXY | 10 gel-caps 100mg total ($38.99), 2 gel-caps 20mg total ($11.99) |
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**PLEASE NOTE: Our strains sometimes change weekly, if we are out of stock we will select the next best strain.
William Stiener –
Too good to be true I thought, This stuff (7oxy) is a game changer… I thew all my prescription pain killer pills away. 7oxy feels better than Vicoden and it lasts longer. I have chronic back pain and FINALLY a natural pain killer that works without the side effects! Thank you Farma Barn, 7oxy has changed my life.
[...]Tammy –
I didn’t like how oxycodone made me feel but needed pain relief after getting 3 pelvic fxs, 7 L-Spine fxs, and sacrum and rib fxs. I was introduced to 7 when the Oxy wasn’t even working anymore.. From the first time I took it I found relief. Approximately 20 minutes to react and it lasted for about 5-6 hrs. Thought it was a fluke but kept up usage.
[...]It has been a God send to navigate this healing journey.❤️?